Robustness has long been recognized as an important parameter for evaluating game-theoretic results, but talk of ‘robustness’ generally remains vague. What we offer here is a graphic measure for a particular kind of robustness (‘matrix robustness’), using a three-dimensional display of the universe of 2 × 2 game theory. In such a measure specific games appear as specific volumes (Prisoner’s Dilemma, Stag Hunt, etc.), allowing a graphic image of the extent of particular game-theoretic effects in terms of those games. The (...) measure also allows for an easy comparison between different effects in terms of matrix robustness. Here we use the measure to compare the robustness of Tit for Tat’s well-known success in spatialized games (Axelrod, R. (1984). The evolution of cooperation . New York: Basic Books; Grim, P. et al. (1998). The philosophical computer: Exploratory essays in philosophical computer modeling . Cambridge, Mass: MIT Press) with the robustness of a recent game-theoretic model of the contact hypothesis regarding prejudice reduction (Grim et al. 2005. Public Affairs Quarterly, 19 , 95–125). (shrink)

We apply spatialized game theory and multi-agent computational modeling as philosophical tools: (1) for assessing the primary social psychological hypothesis regarding prejudice reduction, and (2) for pursuing a deeper understanding of the basic mechanisms of prejudice reduction.

Tumor‐cell diversification mechanisms insure that malignant neoplasms contain diversified tumor‐cell subpopulations. Because of the instability of tumor cell phenotypes, some malignant cells will evolve with the most favorable properties for their progression to highly metastatic cells. The rates of cellular phenotypic diversification vary greatly among different tumors, and they are probably modulated, in part, by genetic and chromosome defects and by epigenetic events that may vary widely depending upon the nature of the tumor cells and their microenvironments. As tumor diversification (...) and selection proceed, the most malignant cell subpopulations may eventually become dominant and gradually lose their microenvironmental responsiveness. Tumor‐cell diversification mechanisms may be similar or identical to normal, developmentally regulated diversification mechanisms that are used during embryonic cell diversification and differentiation. (shrink)

Our aims are to set forth a multiprinciple system for selecting among clinical trials competing for limited space in an immunotherapy production facility that supplies products under investigation by scientific investigators; defend this system by appealing to justice principles; and illustrate our proposal by showing how it might be implemented. Our overarching aim is to assist manufacturers of immunotherapeutic products and other potentially breakthrough experimental therapies with the ethical task of prioritizing requests from scientific investigators when production capacity is limited.

Height preferences reflecting positive assortative mating for height—wherein an individual’s own height positively predicts the preferred height of their mate—have been observed in several distinct human populations and are thought to increase reproductive fitness. However, the extent to which assortative preferences for height differ strategically for short-term versus long-term relationship partners, as they do for numerous other indices of mate quality, remains unclear. We explore this possibility in a large representative sample of over 500 men and women aged 15–77 from (...) Canada, Cuba, Norway and the United States. Participants’ own heights were measured, and they indicated their height preferences for a long-term and short-term mate using graphic stimuli containing metric indices. Replicating the “male-taller norm,” participants on average preferred taller-than-average male mates, and shorter-than-average female mates. Positive assortative preferences for height were observed across sexes and samples, however the strength of these height preferences varied with relationship context for men, and not for women. Taller men preferred relatively shorter women for short-term relationships than for long-term relationships, indicating stronger assortative preferences for height in a long-term context. These results provide preliminary evidence that, in addition to mate preferences for other physical traits related to mate quality such as masculinity in the body, face, and voice, assortative preferences for height do vary as a function of expected relationship length, but this was surprisingly only observed in preferences for female height. (shrink)

In response to growing concern in the 1980s about the quality of public education across the United States, a tremendous amount of energy was expended by organizations such as the Holmes Group and the Carnegie Forum to organize professional development schools or “partner schools” for teacher education. On the surface, the concept of partnering is simple; however, the practice is very costly, complex, and difficult. In _Schooling, Democracy, and the Quest for Wisdom_, Robert V. Bullough, Jr. and John R. (...) Rosenberg examine the concept of partnering through various lenses and they address what they think are the major issues that need to be, but rarely are, discussed by thousands of educators in the U.S. who are involved and invested in university-public school partnerships. Ultimately, they assert that the conversation around partnering needs re-centering, refreshing, and re-theorizing. (shrink)

Contemporary scientific research and public policy are not in agreement over what should be done to address the dangers that result from the drop in driving performance that occurs as a driver talks on a cellular phone. One response to this threat to traffic safety has been the banning in a number of countries and some states in the USA of handheld cell phone use while driving. However, research shows that the use of hands-free phones (such as headsets and dashboard-mounted (...) speakers) also accompanies a drop, leading some to recommend regulation of both kinds of mobile phones. In what follows, I draw out the accounts of the driving impairment associated with phone use implicit in research and policy and develop an alternative account grounded in philosophical considerations. Building on work in a school of thought called postphenomenology, I review and expand concepts useful for articulating human bodily and perceptual relations to technology. By applying these ideas to the case of driving while talking on the phone, I offer an account of the drop in driving performance which focuses on the embodied relationships users develop with the car and the phone, and I consider implications for research and policy. (shrink)

In a future world of ubiquitous computing, in which humans interact with computerized technologies even more frequently and in even more situations than today, interface design will have increased importance. One feature of interface that I argue will be especially relevant is what I call abstract relational strategies. This refers to an approach (in both a bodily and conceptual sense) toward the use of a technology, an approach that is general enough to be applied in many different concrete scenarios. Such (...) an abstract manner of approach is relevant, for example, when an interface design for a device to which users are already accustomed is applied to an entirely different device (such as a device used for a completely different purpose). To articulate this idea, I explore the history of keyboards, and consider how the habits of interface with one kind (e.g., piano keyboards) have historically enabled some users to approach other technologies fitted with similar keyboard interface (e.g., typewriters, electronic instrumentation). I conclude by brainstorming ways that abstract relational strategies, applicable to a variety of different devices, will have increased importance in a future world in which computing is even more ubiquitous than today. (shrink)

Defenders of educational frog dissection tend to emphasize the claim that computer-simulated alternatives cannot replicate the same exact experience of slicing open a frog, with all its queasy and visceral impact. Without denying that point, I argue that this is not the only educational standard against which computer-simulated dissection should be evaluated. When real-world frog dissection is analyzed as a concrete technological practice rather than an assumed ideal, the particular educational advantages distinct to real-world dissection and virtual dissection can be (...) enumerated and compared. Building on the work of John Dewey and Don Ihde, I explore the still-expanding advantages of computer-simulated dissection, and in this proper context of comparison it becomes clear that virtual alternatives are increasingly the more educationally beneficial option. (shrink)

Mouse embryonic stem cells have an unlimited lifespan in cultures if they are prevented from differentiating. After differentiating, they produce cells which divide only a limited number of times. These changes seen in cultures parallel events that occur in the developing embryo, where immortal embryonic cells differentiate and produce mortal somatic ones. The data strongly suggest that differentiation initiates senescence, but this view entails additional assumptions in order to explain how the highly differentiated sexual gametes manage to remain potentially immortal. (...) Cells differentiate by blocking expression from large parts of their genome and it is suggested that losses or gains of genetic totipotency determine cellular lifespans. Cells destined to be somatic do not regain totipotency and senesce, while germ‐line cells regain complete genome expression and immortality after meiosis and gamete fusions. Losses of genetic totipotency could induce senescence by lowering the levels of repair and maintenance enzymes. (shrink)

Ideas developed within the philosophical tradition of phenomenology can be used to describe the experience of talking on the phone. In particular, I build on a contemporary brand of phenomenology called “postphenomenology,” a school of thought which specializes in the analysis of the relationships that form between users and technologies. Three central concepts are reviewed and developed: transparency, sedimentation, and what I call “field composition.” These concepts can be used for the description of the way that the content of a (...) telephone conversation can come to stand forward and capture a user’s overall field of awareness. I suggest that this account of the experience of the telephone can be useful for analyzing issues in scientific research and public policy regarding the topic of using the phone while driving. (shrink)

Don Ihde is one of the world's foremost thinkers on the place of technologies in our lives. Over the course of a long career, he has built a unique and useful perspective by expanding on phenomenological and American pragmatist philosophy and has developed wide-ranging insights and conceptual tools for describing the details of our experience across the various areas of human activity, including scientific practice, anthropological history, computer interface, design, art history, and the technologies of everyday life. The Critical Ihde (...) brings together many of Ihde's most influential writings, as well as a number of under-recognized gems. Across these works are examples of his influential contributions to the phenomenology of human auditory and visual experience, his foundational work on the phenomenology of technology, and his thoughts on the technologies of scientific practice, including laboratory and medical imaging. Further, these chapters reveal the development of "postphenomenology," Ihde's original philosophical perspective, one that continues to flourish today across the work of a growing interdisciplinary and international collective of scholars. (shrink)

A central question in philosophical and sociological accounts of technology is how the agency of technologies should be conceived, that is, how to understand their constitutive roles in the actions performed by assemblages of humans and artifacts. To address this question, I build on the suggestion that a helpful perspective can be gained by amalgamating “actor-network theory” and “postphenomenological” accounts. The idea is that only a combined account can confront both the nuances of human experiential relationships with technology on which (...) postphenomenology specializes, and also the chains of interactions between numerous technologies and humans that actor-network theory can address. To perform this amalgamation, however, several technical adjustments to these theories are required. The central change I develop here is to the postphenomenological notion of “multistability,” i.e., the claim that a technology can be used for multiple purposes through different contexts. I expand the postphenomenological framework through the development of a method called “variational cross-examination,” which involves critically contrasting the various stabilities of a multistable technology for the purpose of exploring how a particular stability has come to dominate. As a guiding example, I explore the case of the everyday public bench. The agency of this “mundane artifact,” as actor-network theorist Bruno Latour would call it, cannot be accounted for by either postphenomenology or actor-network theory alone. (shrink)

This special report is published in commemoration of the fiftieth anniversary of the “Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death,” a landmark document that proposed a new way to define death, with implications that advanced the field of organ transplantation. This remarkable success notwithstanding, the concept has raised lasting questions about what it means to be dead. Is death defined in terms of the biological failure of the organism to (...) maintain integrated functioning? Can death be declared on the basis of severe neurological injury even when biological functions remain intact? Is death essentially a social construct that can be defined in different ways, based on human judgment? These issues, and more, are discussed and debated in this report by leading experts in the field, many of whom have been engaged with this topic for decades. (shrink)

How should we understand postphenomenological methodology? Postphenomenology is a research perspective which builds on phenomenological and pragmatist philosophy to explore human–technology relations, but one with open methodological questions. Here, I offer some thoughts on the epistemological processes that should be (and often implicitly may be) at work in this research. In particular, I am concerned with postphenomenological research on technological “multistability,” i.e., a device’s ever-present capacity to be used for a variety of purposes, and to always be meaningful in multiple (...) ways. I develop a methodology called “variational cross-examination,” which entails the critical contrast of a device’s various stabilities. As a set of instructive examples, I draw on my own line of research on the politics of public spaces, and especially the critique of anti-homeless design. (shrink)

Social isolation and loneliness are growing concerns around the globe that put people at increased risk of disease and early death. One much‐touted approach to addressing them is deploying artificially intelligent agents to serve as companions for socially isolated and lonely people. Focusing on digital humans, we consider evidence and ethical arguments for and against this approach. We set forth and defend public health policies that respond to concerns about replacing humans, establishing inferior relationships, algorithmic bias, distributive justice, and data (...) privacy. (shrink)

A discussion is emerging within the contemporary philosophy of technology over issues of discrimination through design. My suggestion is that a productive way to approach this topic is through a combination of insights from the postphenomenological and critical constructivist perspectives. In particular, I recommend that we build on the postphenomenological notion of “multistability” and conceive of instances of discrimination through design as a kind of discriminatory “stability,” one possible instantiation of a device that could be usefully contrasted with others. Through (...) the adoption of ideas from critical constructivism and postphenomenology, it is possible to draw out some of the features of discriminatory stabilities, including how systems of bias can go unnoticed, especially by those not targeted by them. These ideas could be of use in the identification of ways that unjust systematic biases become set within dominant culture, designed into technologies, sedimented within individual bodily-perceptual habits, and even constructed into prevailing senses of reason. As a practical contribution to this ongoing discussion, I identify a distinction that can be made between two broad categories of discrimination via technology: 1. that occurring along what could be called “an axis of difference,” and 2. “an axis of usage.” In the former, discriminatory efforts occur as different users are advantaged and disadvantaged by a device, even as they use it for similar purposes. In the latter, discriminatory effects occur as the particular usage of a technology preferred by a vulnerable group is shut down through design choices. Although the various emerging discussions on technology and discrimination each tend to gravitate toward analysis along one of these axes, it will of course be important to keep our eyes on the variety of ways that biases are faced by the vulnerable. (shrink)

The emerging school of thought called “postphenomenology” offers a distinct understanding of the ways that people experience technology usage. This perspective combines insights from the philosophical tradition of phenomenology with commitments to the anti-essentialism and nonfoundationalism of American pragmatism. One of postphenomenology’s central positions is that technologies always remain “multistable,” i.e., subject to different uses and meanings. But I suggest that as this perspective matures, philosophical problems are emerging around the notion of multistability, what I call “the problem of invariance” (...) and “the problem of grounding.” These problems point out things that remain unclear within the postphenomenological framework, such as how it handles structural claims regarding a technology’s various stabilities, and how it grounds its claims. How can postphenomenology make structural claims about technology and yet remain anti-essentializing? And on what epistemological basis does it ground its claims about human-technology relations? The paper concludes with a series of prescriptions that, if followed, enable postphenomenology to make edifying claims about technology, all while avoiding the problems of invariance and grounding, and maintaining its commitments to anti-essentialism and nonfoundationalism. (shrink)

The philosophical tradition of phenomenology, with its focus on human bodily perception, can be used to explore the ways scientific instrumentation shapes a user’s experience. Building on Don Ihde’s account of technological embodiment, I develop a framework of concepts for articulating the experience of image interpretation in science. These concepts can be of practical value to the analysis of scientific debates over image interpretation for the ways they draw out the relationships between the image-making processes and the rival scientific explanations (...) of image content. As a guiding example, I explore a contemporary debate over images of the surface of Mars which reveal a landmass that resembles river delta formations on Earth, and which thus has important implications for the history of Martian climate and water flow. The phenomenological framework I develop can be used to help evaluate the different interpretations on offer for these images, and to analyze the roles in this discussion played by spacecraft equipped with cameras and laser and thermal imaging devices. (shrink)

The experience of computer use can be productively articulated with concepts developed in the phenomenological tradition of philosophy. Building on the insights of classical phenomenologists, Ihde has advanced a sophisticated view of the ways humans relate to technology. I review and expand on his notions of “technological mediation,” “embodiment,” and “multistability,” and apply them to the experience of computer interface. In particular, I explore the experience of using a computer that fails to work properly. A revealing example is the experience (...) of a user who suddenly and unexpectedly encounters a slowly-loading webpage while using the Internet. This phenomenological framework provides an account of the ways a suddenly failing technology changes our relationships to the device, to the world, and to ourselves, and it also suggests how this experience can be usefully reconceptualized. (shrink)

An emerging philosophical perspective called “postphenomenology,” which offers reflection upon human relations to technology, has the potential to increase our understanding of the functions performed by imaging technologies in scientific practice. In what follows, I review some relevant insights and expand them for use in the concrete analysis of practices of image interpretation in science. As a guiding example, I explore how these insights bear upon a contemporary debate in space science over images of the fossilized remains of a river (...) delta on the surface of Mars. These considerations include an analysis of the ways that the objects of study are transformed by the mediating imaging technologies, such as the Mars Orbiter Camera. (shrink)

It can sometimes be difficult to think about “everyday” objects, those things we are so familiar with that they become taken-for-granted aspects of the backdrop of our world. But what if those objects, despite their everydayness, are politically fraught and call for closer examination? I suggest that insights from two contemporary perspectives, postphenomenology and actor-network theory, are useful for drawing out the experiential, social, and political dynamics of everyday things. In this paper, I review and resituate several key concepts from (...) these two theoretical frameworks and outline a method for using them together for the evaluation of technology. As a guiding example, I explore a paradigmatic everyday device: fire hydrants. Despite their everyday character, hydrants fulfill multiple social roles, some of them loaded with difficult and important political implications. (shrink)

A caregiver from the dominant U.S. culture and a patient from a very different culture can resolve cross‐cultural disputes about treatment, not by compromising important values, but by focusing on the patient's goals.

Book reviewed in this article: Medicine and Culture: Varieties of Treatment in the United States, England, West Germany, and France. By Lynn Payer. Health Care Systems: Moral Conflicts in European and American Public Policy. Edited by Hans‐Martin Sass and Robert U. Massey.

‘The problem with simulations is that they are doomed to succeed.’ So runs a common criticism of simulations—that they can be used to ‘prove’ anything and are thus of little or no scientific value. While this particular objection represents a minority view, especially among those who work with simulations in a scientific context, it raises a difficult question: what standards should we use to differentiate a simulation that fails from one that succeeds? In this paper we build on a structural (...) analysis of simulation developed in previous work to provide an evaluative account of the variety of ways in which simulations do fail. We expand the structural analysis in terms of the relationship between a simulation and its real-world target emphasizing the important role of aspects intended to correspond and also those specifically intended not to correspond to reality. The result is an outline both of the ways in which simulations can fail and the scientific importance of those various forms of failure. (shrink)

Thinkers from a variety of fields analyze the roles of imaging technologies in science and consider their implications for many issues, from our conception of selfhood to the authority of science. In what follows, I encourage scholars to develop an applied philosophy of imaging, that is, to collect these analyses of scientific imaging and to reflect on how they can be made useful for ongoing scientific work. As an example of this effort, I review concepts developed in Don Ihde’s phenomenology (...) of technology and refigure them for use in the analysis of scientific practice. These concepts are useful for drawing out the details of the interpretive frameworks scientists bring to laboratory images. Next, I apply these ideas to a contemporary debate in neurobiology over the interpretation of images of neurons which have been frozen at the moment of transmitter release. This reveals directions for further thought for the study of neurotransmission. (shrink)

During the mid-nineteenth century the annual tuberculosis mortality in the penitentiaries at Auburn, N.Y., Boston, and Philadelphia exceeded 10 percent of the inmate population. At the beginning of the sanatorium era, 80 percent of the prison deaths were attributed to TB. As the mountain air was “commonly known” to be healthful, the first prison sanatorium was opened in the mountains near Dannemora, N.Y. in 1904. It served to isolate contagious prison inmates until the advent of effective chemotherapy for the disease (...) in the 1950’s. Early antibiotic therapy for TB was such a great success that the public health aspects of TB in prisons remained dormant for the next 40 years.In 1991, a correctional officer from Auburn Correctional Facility in Auburn, New York died as a result of multidrug-resistant TB. He had been posted to care for hospitalized patients, from whom he acquired his disease. This death, and the transmission of TB infection to health care workers in the same hospital, brought the nature and extent of modern inmate medical care into finer focus. (shrink)

The postphenomenological framework of concepts—and especially the version utilized by the founder of this school of thought, Don Ihde—has proven useful for puncturing others’ totalizing or otherwise overgeneralizing claims about technology. However, does this specialization in deflating hype leave this perspective unable to identify the kinds of technological patterns necessary for contributing to activist interventions and political critique? Put differently, the postphenomenological perspective is committed to the study of concrete human-technology relations, and it eschews essentialist and fundamentalizing accounts of technology. (...) Do these commitments render it incapable of providing general assessments of our contemporary technological situation? It is my contention that this perspective can indeed be useful for these kinds of critical projects. To do so, we must go beyond Ihde’s personal tendency to utilize postphenomenology mostly for deflating others’ hype, and explore this perspective’s distinctive potential for identifying ways that technologies can become set within problematic patterns of usage and design. My suggestion is that the postphenomenological notion of “multistability” can play a helpful role in these efforts, especially when combined with a conception of local, rather than totalizing, stabilizations of human-technology relationships. (shrink)

Is simulation some new kind of science? We argue that instead simulation fits smoothly into existing scientific practice, but does so in several importantly different ways. Simulations in general, and computer simulations in particular, ought to be understood as techniques which, like many scientific techniques, can be employed in the service of various and diverse epistemic goals. We focus our attentions on the way in which simulations can function as (i) explanatory and (ii) predictive tools. We argue that a wide (...) variety of simulations, both computational and physical, are best conceived in terms of a set of common features: initial or input conditions, a mechanism or set of rules, and a set of results or output conditions. Studying simulations in these terms yields a new understanding of their character as well as a body of normative recommendations for the care and feeding of scientific simulations. (shrink)

It is sometimes argued that since it would be absurd to outlaw passenger conversation, we should not regulate the presumably equivalent act of using the phone while driving. To reveal the spuriousness of this argument and to help urge drivers to refrain from using the phone while behind the wheel, we must draw on two decades of data on smartphone-induced driving impairment, and we need to consider ideas from both the postphenomenological and embodied cognition perspectives. In what follows, I expand (...) on the notion of the “cognitive niche” and develop the corollary notion of the “experiential niche” to describe how our surroundings can prompt a particular phenomenological quality and organization to our lived experience. I argue that conceiving of the car as a cognitive-experiential niche is useful for articulating the crucial differences between passenger and smartphone conversation and helps make the case that we must regulate smartphone use while driving. (shrink)